Desmond and Penny. Has to be, I'm almost 100% convinced, to the point that I wish I hadn't read this, because I'm sure enough to almost consider this a big spoiler. We've seen Jack and Kate kiss before, plus it's off-island. And really, what kiss would be more spectacular than Desmond and Penny?

I totally agree... it has to be Penny& Desmond!

Two options. Kate and Jack in LA, when Jack convinces Kate that "We Have to Go Back!" Or Desmond and Penny, when Penny finds the freighter (then Michael blows it up?).

I think it will be Jack kissing Locke...talk about spectacular!!! It's about time Locke got his props for being resourceful and savvy about the true nature of people and the island.

It won't however be a kiss on the lips though. Jack will have to kiss Locke's behind in a scene with the ultimate "I told you so!!!"

See you in another life brotha!!!

I mean there's always the possibility of a Jack and Kate kiss, I think using the word "spectacular" to describe it would be way more than overdoing it

I think that the kiss is between Jack and Juliet...

Ben & Juliet?

Ben & Penny?

Ben & his childhood love who grew up to be...?

Ben & Jack's ex Wife ;} (the father of their child off the island)

"My guess is that it's going to be between Jack and Kate as they finally escape on the helicopter, though it could also happen on the freighter or in a flash forward."

Why would you assume that? Wishful thinking?

Ben and Locke? C'mon...S4 has been nothing but foreplay for these two. What I'm really hoping is that Kate saves Alex from her current predicament and gets a friendly smooch in return...we can all have a dream right?

D

penny rescuing the O6 and then wen the reach HOME desmond and penny will have there happy ever after (spectacular) KISS !!

END OFF ( THIS KISS BUISNESS IS GETTING BORING)

Sawyer and Hurley.

I do not want to ruin the finale for anyone but it is so obvious the last kiss would be shared between jack and Sawyer .. Let us cut through all this time travel, flashbacks and flash-forward nonsense. Lost is ultimately a love story between Jack and Sawyer. Come on I cannot be the only one to see the sexual tension between the two. They intentional put Kate in the middle between them to take the edge off there undeniable passion for one and other. Unfortunately, Sawyer will have to stay behind on the island. The last scene as Jack is getting on the helicopter he gives Sawyer one last look. Then he races toward Sawyer and they finally embrace. Last line will be Jack’s. “I’ll come back for you James.”

Just having a little fun folks

It's gonna be between Locke and his father..... JACOB!!!!! Jacob will kiss him on the forehead and call him son. Fade to black

What about a dramatic Sun & Jin kiss as Sun goes away without Jin?

hmmmm, i've always wondered why i thought Locke was an amazing character. can anyone say..... Dr. Frank-N-Furter?!

"Yes, I'm afraid so, Janet. But isn't it nice?!
JANET: Oh, you beast! You monster! What have you done with Brad?!
FRANK: Oh, well, nothing. (AUDIENCE: Yet!)"

Well color me less than optimistic, but I really cannot imagine any kiss between any of our cast members as one being spectacular.

Understanding a typical writing technique, a spectacular kiss usually comes after a troubled romantic build up. Build ups such as this normally takes several forms but almost always has one theme; that being that the couple has been restrained from one another for whatever reason. It could be separation by mileage, separation by jealousy/anger/disagreement, separation by being part of another couple at the wrong time, separation by not knowing/understanding the other half's feelings, and so forth. It's all a cliche mind you, but that's how the technique works.

Jack/Kate/Sawyer all fit within those guidelines, but it's been put on a back burner so to speak. In other words, the romantic buildup has not been very forward this season as there has only been a half mention of it here and there. I'm doubtful it's a Kate involved kiss.

Juliet/Jack has already been done... after following the above technique, I might add. I wouldn't call that kiss spectacular, but it was a long time in coming and it was such a relief to have it over and done with. ;)

Ben/Annie is doubtful, but possible. There is a slight build up going on this very minute and I would love to see this as THE kiss, but there would need to be more immediate buildup. Typically there is an intense situation just before the occurence. Wow!!! A totally (somewhat unrelated) thought just struck me. Wouldn't it be interesting to find out that the whole reason Ben is doing this time thing is to bring Annie back?! Now a kiss after something so explosive as that would definitely be spectacular. However if that theory is right, we likely wouldn't know that answer until the last season. Shucks.

Jin/Sun is another doubtful one. Their relationship is all emotional and not very physical. I find a hug and kiss for them as a heart warming 'accomplishment', but I wouldn't define that as spectacular. Jin's final kiss will be sad and hopefully not a spectacular event.

Sayid/? is a thought here if I may. Sayid has serious relationship issues. He tends to select only women who are not going to be around for very long, for whatever reason. He is similar to Jack in that respect. Sayid easily falls in love, also like Jack. Could there be a Sayid/someone brewing? There has been no build up at all for him, but that Charlotte is an interesting candidate. Two of his three women had attitudes very similar to hers too, so that makes her even more of a candidate. Of course... he'd have to get off that boat first.

Desmond/Penny is a very likely choice. That one amazingly romantic episode more than qualifies as a build up for such a kiss. A special reunion between those two would be a nice one. The only problem is that I don't believe I personally would find it spectacular. A kiss between these two is to be expected, so it's hardly spectacular.

One that I doubt many are seriously considering that I'd find spectacular is Daniel and ?. No, really. I absolutely adore him and would think his kissing anyone would be a spectacular event. ;)

Okay so if I had to choose one, my money would be on Des/Penny as the couple Cuse is referring to, but I'm crossing my fingers that it is either instead the very unlikely Ben/Annie OR Daniel/?.

Jack and Claire for sure.

The spectacular kiss will be between a young Locke and Ben's girlfriend Annie.

What about Ben & Juliet?